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KMID : 1102220160350010050
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Kidney Research and Clinical Practice
2016 Volume.35 No. 1 p.50 ~ p.54
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Comparison of clinical outcomes between ABO-compatible and ABO-incompatible spousal donor kidney transplantation
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Park Woo-Yeong
Kang Seong-Sik
Park Sung-Bae
Park Ui-Jun
Kim Hyong-Tae
Cho Won-Hyun
Han Seung-Yeup
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Abstract
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Background: Kidney transplantation (KT) is the treatment of choice for end-stage renal disease patients. The spouse is a major donor in living KT. Clinical outcomes of spousal donor KT are not inferior to those of living related donor KT. In this study, we compared clinical outcomes between ABO-compatible (ABOc) and ABOincompatible (ABOi) spousal donor KTs.
Methods: Thirty-two cases of spousal donor KT performed from January 2011 to August 2013 were analyzed retrospectively. Twenty-one ABOc KTs and 11 ABOi KTs were performed. We investigated patient survival, graft survival, acute rejection, graft function, and complications.
Results: During follow-up, patient and graft survival rates were 100% in both groups. There were no significant differences in the incidence of delayed graft function, acute rejection, and the change in graft function between the 2 groups. Medical and surgical complications were not significantly different between the groups.
Conclusion: The clinical outcomes of ABOc and ABOi spousal donor KTs were equivalent. In ABOi KT, an emotionally motivated spousal donor KT may be a good alternative to the problem of the absolute shortage of kidney donations.
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KEYWORD
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Blood group incompatibility, Kidney transplantation, Spouses
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